Search results for "Maternal infection"

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Trans-generational immune priming is constrained by the maternal immune response in an insect.

2012

5 pages; International audience; Immune-challenged vertebrate and invertebrate females can transfer immunity to their off spring. Th is trans-generational immune priming (TGIP) is benefi cial for the off spring if the maternal infection risk persists across generations. However, because immunity is costly, fi tness consequences of TGIP have been found in primed off spring. Furthermore, transferring immunity to off spring may be costly for immune-challenged females who are also carrying the costs of their immune response. A negative relationship between levels of immunity between mothers and off spring might therefore be expected. Consistent with this hypothesis, we show that in the insect, …

0106 biological sciencesOffspringmedia_common.quotation_subjectanimal diseaseschemical and pharmacologic phenomenaInsectBiologyBody size[ SDV.IMM.IA ] Life Sciences [q-bio]/Immunology/Adaptive immunology010603 evolutionary biology01 natural sciences03 medical and health sciencesTrans generationalImmune systemImmunity[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisEcology Evolution Behavior and Systematics030304 developmental biologymedia_common[ SDE.BE ] Environmental Sciences/Biodiversity and Ecology0303 health sciencesbiochemical phenomena metabolism and nutritionMaternal infection[SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunologyImmunologybacteria[SDE.BE]Environmental Sciences/Biodiversity and EcologyPriming (psychology)[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Ophthalmic Outcomes of Congenital Toxoplasmosis Followed Until Adolescence

2014

BACKGROUND: Congenital toxoplasmosis (CT) can elicit severe damage to several organs, especially the eye, and may be manifested at birth or later. We assessed the long-term ocular prognosis in a cohort of congenitally infected children treated according to a standardized protocol and monitored for up to 22 years. METHODS: This prospective study included confirmed cases of CT, which were identified by obligatory antenatal screening at the Lyon (France) reference center between 1987 and 2008. Data obtained through ocular examinations were recorded on a standardized form and confirmed by an independent external committee. Risk factors for retinochoroiditis were identified by using a multivari…

AdultMalePediatricsmedicine.medical_specialtyAdolescentEye DiseasesToxoplasmosis CongenitalCohort StudiesLesionYoung AdultPregnancyHumansMedicineProspective StudiesChildProspective cohort studybusiness.industryProportional hazards modelChorioretinitisInfantmedicine.diseaseCongenital toxoplasmosisMaternal infectionTreatment OutcomeChild PreschoolPregnancy Complications ParasiticPediatrics Perinatology and Child HealthCohortOcular lesionFemaleFrancemedicine.symptombusinessFollow-Up StudiesPediatrics
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